RETRACTED ARTICLE: Single-nucleotide polymorphisms in MTHFR gene related to recurrent abortion

Single-nucleotide polymorphisms are a type of genetic variation that may be utilized to investigate illness vulnerability. Recurrent abortion is linked hereditary thrombophilias, which include various disorders such as the MTHFR thermolabile variation. No link known between these two mutations and risk recurrent spontaneous abortion. It unknown if pregnant women with at losing their baby. Thirty patients were referred this prospective experimental investigation clinical results included repeated abortions. Peripheral blood samples used isolate total genomic DNA. PCR–restriction fragment length polymorphism method Sanger sequencing technique estimate frequency gene in patients. The homozygous heterozygous found 80% 20% among patients, respectively. Two followed sequenced know mutation location. revealed several frameshift seen, includes (insertion, deletion, substations). This study highlighted some evidence might play role relationship Furthermore, we believe anticoagulant medication for individuals during pregnancy result successful pregnancy.